Essays are published here first and go out by email a day later. Pieces marked FIG carry a live figure that the email edition cannot render.
2026
Aug 06 Superpower FIG Biomarkers are consumer lead generators. Aug 06 Oura FIG Consumer devices are on their way. Jul 15 Where the money actually goes in a clinical trial FIG A new drug is said to cost about two billion dollars. Follow a hundred companies through the pipeline and you can see why — and it isn't the science that's expensive, it's the failure.